Tolerance and adaptation to dietary fiber linked to Bifidobacterium longum

Research from Synbiotic Health co-founder Prof. Jens Walter and collaborators showed that consumers can ‘adapt’ to high doses of arabinoxylan, an emerging prebiotic fiber.

In a new study, participants consumed high doses of arabinoxylan experienced symptoms for the first 3 weeks of the trial, but by the 6th week, symptoms had returned to baseline. Interestingly, tolerance to arabinoxylan was linked to increased levels of Bifidobacterium longum in the gut.

This work, published in Gut Microbes, forms an important basis for the development of personalized microbiome-targeted strategies. In a collaboration between APC Microbiome Ireland and Synbiotic Health, the arabinoxylan-enriched strains of B. longum are now being studied for next-generation probiotic and synergistic synbiotic applications.

Read the published paper here.