New paper describes the complete genome of B. adolescentis iVS-1®

Scientists from Synbiotic Health have published the complete genome of B. adolescentis iVS-1® in the ASM journal, Microbiology Resource Announcements. The paper, published in December 2023, reveals novel traits for this important probiotic microbe.

Although the draft genome of B. adolescentis iVS-1® was obtained several years ago, now the complete genome sequence has filled in the gaps. The paper reports that iVS-1® contains multiple genes encoding for lactose metabolism and other potentially beneficial traits, including production of folate and gamma-aminobutyric acid (GABA). This strain also contains stress response genes, as well as the metabolic capacity to consume a wide variety of carbohydrates, including FODMAPs (which cause digestive problems in those with irritable bowel syndrome).

The company scientists hope the complete genome will help shape future clinical trials on this important, emerging strain.

Read the full paper here.